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BeautyBeginswithBiology.

Advanced lab testing reveals what’s happening beneath the surface - guiding physician-led hormone care, customized supplements, and education on emerging peptide science.

SCIENCE NEVER LOOKED THIS GOOD!
  • 50+ Biomarkers analysedAdvanced lab testing for a deeper understanding of your biology.
  • Physician-led carePersonalized plans reviewed and guided by medical experts.
  • Ongoing lab monitoringRegular testing and review to ensure your plan evolves with your biology.
  • Personalized to youCare and recommendations tailored to your unique biology, goals, and lifestyle.

How Hot by Science Works

  1. 01

    Build Your Biology Profile

    Complete a health assessment and laboratory testing analyzing 50+ biomarkers across hormones, metabolism, and overall health to build a detailed picture of your biology.

  2. 02

    Receive Your Personalized Care Plan

    A physician reviews your health history and laboratory results to create a tailored plan that may include hormone optimization and customized supplements, aligned with your biology and goals.

  3. 03

    Start Your Program

    Hormone care plan from a physician

    a physician reviews your results and creates a care plan tailored to what you need.

    Supplement pack customized for you

    tailored to your biology and goals.

  4. Explore HBS Peptide Research

    Through our IRB-approved observational study, we collect biological data and self-reported experiences from people using peptides and small molecules. Explore our findings, including which peptides people with similar biological profiles reported to be helpful. If you already use peptides or small molecules, consider sharing your experience to our study to help advance knowledge.

  5. 04

    Ongoing Care: Review, Refine, Repeat

    Once treatment begins, follow-up laboratory testing and physician review occur every three months to monitor progress, refine your plan, and keep your care plan aligned with your evolving biology.

Your care starts with your biology

We start with labs and get to the root of what your body needs.
Your results determine the care plan and membership you need.

Start Here

Initial Evaluation + Labs

Comprehensive evaluation and lab testing to understand your hormones and overall health.

One-time payment$165Includes medical physician review
Your results are reviewed
If no prescription is needed

HBS Membership

$39/ month

  • Care team chat access
  • Labs every 6 months
  • Ongoing support
  • Peptide education
If hormone therapy is prescribed

Hormone Care Membership

$165/ month

  • Prescribed hormone therapy
  • Care team chat access
  • Labs every 3 months
  • Ongoing physician-guided care

Built by Physicians. Driven by Biology.

Founded by reproductive endocrinologist Dr. Arnold Mahesan and entrepreneur Roxy Earle, Hot by Science grew from the intersection of his clinical experience and her personal journey.

Together, they created a platform combining physician-guided care and structured peptide research, built on the belief that meaningful change begins with understanding and optimizing biology.